Open AccessMaternal Benzophenone Exposure Impairs Hippocampus Development and Cognitive Function in Mouse Offspring (Adv. Sci. 23/2021)
Author(s) -
Cui Fengzhen,
Pan Qingfei,
Wang Siyi,
Zhao Faming,
Wang Runxin,
Zhang Tingting,
Song Yaying,
He Jun,
Zhang Haolin,
Weng Qiang,
Jin Yang,
Xia Wei,
Li Yuanyuan,
Yang GuoYuan,
De Vos Winnok H.,
Timmermans JeanPierre,
Xu Shunqing,
Tang Yaohui,
Sheng Xia
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170157
Subject(s) - offspring , benzophenone , pregnancy , neuroinflammation , hippocampus , endoplasmic reticulum , metabolite , cognition , medicine , physiology , chemistry , endocrinology , biology , psychiatry , biochemistry , photochemistry , inflammation , genetics
Maternal Benzophenone Exposure In article number 2102686 by Shunqing Xu, Yaohui Tang, Xia Sheng, and co‐workers, it is reported that maternal exposure to benzophenone and its major metabolite 4‐hydroxybenzophenone during pregnancy causes endoplasmic reticulum proteotoxicity and neuroinflammation, which lead to cognitive dysfunction and neurodevelopmental toxicity in offspring mice. This alerts that the excessive use of personal care products during pregnancy may impair child's neurodevelopment.