Open AccessErythrocytes, a New Contributor to Age‐Associated Loss of Blood–Brain Barrier Integrity (Adv. Sci. 20/2021)
Author(s) -
Amiri Payam,
DeCastro Jonalyn,
Littig Joshua,
Lu HsiangWei,
Liu Chao,
Conboy Irina,
Aran Kiana
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170137
Subject(s) - blood–brain barrier , personal integrity , medicine , neuroscience , central nervous system , biology , psychology , social psychology
Blood–Brain Barriers In article number 2101912, Irina Conboy, Kiana Aran, and co‐workers show that erythrocytes derived from old mammals (mice and people) have deleterious effects on the integrity of the blood‐brain barrier, when compared to the young donor cells. This previously unknown change in erythrocyte behavior unveils a new mechanism of age‐associated neurological decline. Image credits: Ella Maru Studio.