Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing (Adv. Sci. 18/2021) | Zendy

Schirmer Lucas | Zendy; Atallah Passant | Zendy; Freudenberg Uwe | Zendy; Werner Carsten | Zendy

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Chemokine‐Capturing Wound Contact Layer Rescues Dermal Healing (Adv. Sci. 18/2021)

Author(s) -

Schirmer Lucas,

Atallah Passant,

Freudenberg Uwe,

Werner Carsten

Publication year - 2021

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.202170114

Subject(s) - wound healing , inflammation , chemokine , medicine , immunology

Wound Healing Excessive inflammation often impedes the healing of chronic wounds. In article number 2100293, Lucas Schirmer, Carsten Werner, and co‐workers report a glycosaminoglycan hydrogelcoated wound contact layer capable of selectively sequestering pro‐inflammatory chemokines. A large animal model of human wound healing disorders confirms that the approach dampens inflammation without affecting pro‐regenerative growth factors, thus expanding the scope of a new anti‐inflammatory therapy toward clinical use.

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