Open AccessIntravital Whole‐Process Monitoring Thermo‐Chemotherapy Via 2D Silicon Nanoplatform: A Macro Guidance and Long‐Term Microscopic Precise Imaging Strategy (Adv. Sci. 16/2021)
Author(s) -
Huang Doudou,
Wang Guangxing,
Mao Jingsong,
Liu Chunlei,
Fan Zhongxiong,
Zhang Yunrui,
Zhang Bei,
Zhao Yang,
Dai Cuixia,
He Yaqin,
Ma Heng,
Liu Gang,
Chen Xiaoyuan,
Zhao Qingliang
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170096
Subject(s) - chemotherapy , process (computing) , materials science , glioma , cancer research , nanotechnology , biomedical engineering , computer science , medicine , operating system
Thermo‐Chemotherapy A promising biocompatible nanotheranostics agent based on chemotherapeutic drug 5‐fluorouracil and 2D silicon nanosheets is developed for synergistic thermo‐chemotherapy strategy. The tumor tissue functional parameters, including SaO 2 , HbT, micro microvascular morphology, and hemodynamics, are dynamically monitored by multimodal PA/OCTA/LS imaging strategy to accurately evaluate overall therapeutic effects. This novel strategy exhibits prominent therapeutic efficiency on malignant glioma U87‐MG. More details can be found in article number 2101242 by Heng Ma, Qingliang Zhao, and co‐workers.