Open AccessA Lubricated Nonimmunogenic Neural Probe for Acute Insertion Trauma Minimization and Long‐Term Signal Recording (Adv. Sci. 15/2021)
Author(s) -
Lee Yeontaek,
Shin Hyogeun,
Lee Dongwon,
Choi Sungah,
Cho IlJoo,
Seo Jungmok
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170095
Subject(s) - immune system , signal (programming language) , materials science , biomedical engineering , inflammation , nanotechnology , sensitivity (control systems) , medicine , immunology , computer science , electronic engineering , engineering , programming language
Lubricated Immune‐Stealth Probe Surface The practical application of implantable neural probes has been limited due to a negative immune response that deteriorates signal sensitivity over time. In article number 2100231, Il‐Joo Cho, Jungmok Seo, and co‐workers report lubricated immune‐stealth probe surface (LIPS) with non‐immunogenic properties. Near frictionless and anti‐biofouling properties of LIPS reduce acute‐ and chronic‐inflammation, extending neural probe's longevity from 8 to 16 weeks.