Endosseous Implants: In Situ Regulation of Macrophage Polarization to Enhance Osseointegration Under Diabetic Conditions Using Injectable Silk/Sitagliptin Gel Scaffolds (Adv. Sci. 3/2021)
Author(s) -
Xiang Geng,
Liu Keyin,
Wang Tianji,
Hu Xiaofan,
Wang Jing,
Gao Zhiheng,
Lei Wei,
Feng Yafei,
Tao Tiger H.
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170015
Subject(s) - osseointegration , macrophage polarization , sitagliptin , silk , materials science , biomedical engineering , implant , chemistry , macrophage , nanotechnology , dentistry , medicine , in vitro , composite material , biochemistry , diabetes mellitus , surgery , endocrinology , type 2 diabetes
In article number 2002328, Yafei Feng, Tiger H. Tao, Wei Lei, and co‐workers report a silk gel scaffold loaded with sitagliptin to in situ regulate macrophage polarization from M1 to M2 phenotypes and improve osteointegration of endosseous implants at the bone‐implant interface under diabetic conditions.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom