Open AccessCardiac Repair: Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury (Adv. Sci. 1/2021)
Author(s) -
Liu Mengrui,
Lutz Halle,
Zhu Dashuai,
Huang Ke,
Li Zhenhua,
Dinh PhuongUyen C.,
Gao Junqing,
Zhang Yi,
Cheng Ke
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170005
Subject(s) - inhalation , medicine , stem cell , antibody , immunology , cancer research , microbiology and biotechnology , anesthesia , biology
Like the idiom of “borrow arrows with thatched boats” (chinese ), inhaled bispecific antibodies lodge on to lung resident platelets (thatched boats) to “borrow” stem cells (arrows) from the lungs and transport them to the injured heart for cardiac repair, as described by Junqing Gao, Yi Zhang, Ke Chang, and co‐workers in article number 2002127.