Open AccessIntravascular Embolization: Nanocomposite Hydrogel with Tantalum Microparticles for Rapid Endovascular Hemostasis (Adv. Sci. 1/2021)
Author(s) -
Albadawi Hassan,
Altun Izzet,
Hu Jingjie,
Zhang Zefu,
Panda Anshuman,
Kim HanJun,
Khademhosseini Ali,
Oklu Rahmi
Publication year - 2021
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202170002
Subject(s) - hemostasis , medicine , embolization , tantalum , radiology , bleed , surgery , materials science , metallurgy
Endovascular embolization is performed to treat various vascular diseases including hemorrhage, aneurysms, and vascular malformations. In article number 2003327, Rahmi Oklu, Ali Khademhosseini, and co‐workers report a tantalum microparticle‐loaded shear‐thinning gel embolic material (Ta‐GEM) that can be rapidly delivered into diseased arteries using clinical catheters to achieve rapid hemostasis. The cover image shows the swine pelvic vasculature, with both iliac arteries demonstrating vascular hemorrhage. The left side is successfully occluded using the gel embolic material (GEM), whereas the right side received coil embolization (the standard treatment today) where blood continues to bleed through the coils.