Open AccessSARS‐CoV‐2: Bioinspired DNase‐I‐Coated Melanin‐Like Nanospheres for Modulation of Infection‐Associated NETosis Dysregulation (Adv. Sci. 23/2020)
Author(s) -
Park Hee Ho,
Park Wooram,
Lee Yun Young,
Kim Hyelim,
Seo Hee Seung,
Choi Dong Wook,
Kwon HoKeun,
Na Dong Hee,
Kim TaeHyung,
Choy Young Bin,
Ahn June Hong,
Lee Wonhwa,
Park Chun Gwon
Publication year - 2020
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202070132
Subject(s) - sepsis , immunology , microbiology and biotechnology , medicine , biology
In article number 2001940, June Hong Ahn, Wonhwa Lee, Chun Gwon Park, and co‐workers demonstrate that NETosis factor can be a potential therapeutic target for the treatment of SARS‐CoV‐2‐induced sepsis. DNase‐I coated melanin‐like nanospheres (DNase‐I pMNSs) show excellent stability, modulation of sepsis‐associated NETosis dysregulation and prevention of further disease progression.