Glycogen Metabolism: IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway (Adv. Sci. 19/2020) | Zendy

Zhu Xiaopeng | Zendy; Yao Ting | Zendy; Wang Ru | Zendy; Guo Shanshan | Zendy; Wang Xin | Zendy; Zhou Zhenqi | Zendy; Zhang Yan | Zendy; Zhuo Xiaozhen | Zendy; Wang Ruitao | Zendy; Li John Zhong | Zendy; Liu Tiemin | Zendy; Kong Xingxing | Zendy

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Glycogen Metabolism: IRF4 in Skeletal Muscle Regulates Exercise Capacity via PTG/Glycogen Pathway (Adv. Sci. 19/2020)

Author(s) -

Zhu Xiaopeng,

Yao Ting,

Wang Ru,

Guo Shanshan,

Wang Xin,

Zhou Zhenqi,

Zhang Yan,

Zhuo Xiaozhen,

Wang Ruitao,

Li John Zhong,

Liu Tiemin,

Kong Xingxing

Publication year - 2020

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.202070108

Subject(s) - glycogen , glycogen synthase , skeletal muscle , irf4 , metabolism , endocrinology , glycogen debranching enzyme , medicine , chemistry , biology , biochemistry , transcription factor , gene

Little is known about how glycogen metabolism is manipulated during exercise. In article number 2001502, John Zhong Li, Tiemin Liu, Xingxing Kong, and coworkers identify that interferon regulatory factor 4 (IRF4) in skeletal muscle regulates glycogen metabolism and subsequent exercise capacity. This work reveals a regulatory pathway including IRF4/protein targeting to glycogen (PTG)/glycogen synthesis on controlling exercise capacity.

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