Open AccessNanomedicine: A Nanomedicine Fabricated from Gold Nanoparticles‐Decorated Metal–Organic Framework for Cascade Chemo/Chemodynamic Cancer Therapy (Adv. Sci. 17/2020)
Author(s) -
Ding Yuan,
Xu Hao,
Xu Chang,
Tong Zongrui,
Zhang Sitong,
Bai Yang,
Chen Yining,
Xu Qianhui,
Zhou Liuzhi,
Ding Hao,
Sun Zhongquan,
Yan Sheng,
Mao Zhengwei,
Wang Weilin
Publication year - 2020
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202070098
Subject(s) - nanomedicine , colloidal gold , nanoparticle , nanotechnology , materials science , cancer therapy , cancer , medicine
In article number 2001060, Sheng Yan, Zhengwei Mao, Weilin Wang, and co‐workers fabricate a hybrid nanomedicine (Au/FeMOF@CPT NPs) using metal–organic framework (MOF) nanoparticles and gold nanoparticles (Au NPs) as building blocks. The intracellular glucose can be oxidized by Au NPs to produce hydrogen dioxide, which is further utilized as chemical fuel for the Fenton reaction, thus realizing the synergistic anticancer efficacy.