Open AccessAntibiotic Resistance: Photo‐Disassembly of Membrane Microdomains Revives Conventional Antibiotics against MRSA (Adv. Sci. 6/2020)
Author(s) -
Hui Jie,
Dong PuTing,
Liang Lijia,
Mandal Taraknath,
Li Junjie,
Ulloa Erlinda R.,
Zhan Yuewei,
Jusuf Sebastian,
Zong Cheng,
Seleem Mohamed N.,
Liu George Y.,
Cui Qiang,
Cheng JiXin
Publication year - 2020
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.202070035
Subject(s) - staphylococcus aureus , antibiotics , antibiotic resistance , microbiology and biotechnology , methicillin resistant staphylococcus aureus , chemistry , chromophore , biology , bacteria , photochemistry , genetics
In article number 1903117, Ji‐Xin Cheng and co‐workers report an endogenous chromophore‐based phototherapy platform to combat antibiotic‐resistance Staphylococcus aureus infections. Functional membrane microdomains of Staphylococcus aureus are catastrophically disrupted via photochemical decomposition of membrane‐bound carotenoid pigment, staphyloxanthin, thus reviving a broad spectrum of conventional antibiotics against Staphylococcus aureus .