Open AccessTissue Expansion: Scalable and Isotropic Expansion of Tissues with Simply Tunable Expansion Ratio (Adv. Sci. 22/2019)
Author(s) -
Park HanEol,
Choi Dongkil,
Park Ji Su,
Sim Changgon,
Park Sohyun,
Kang Sunah,
Yim Hyunsoo,
Lee Myungsun,
Kim Jaeyoun,
Pac Jinyoung,
Rhee Kunsoo,
Lee Junho,
Lee Yunjong,
Lee Yan,
Kim SungYon
Publication year - 2019
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201970131
Subject(s) - isotropy , expansion ratio , materials science , tissue expansion , zoom , biomedical engineering , composite material , optics , physics , medicine , surgery , lens (geology)
In article number 1901673, Yan Lee, Sung‐Yon Kim, and co‐workers develop ZOOM, a new tissue expansion technique based on the hydrogel conversion reaction, to enable scalable and isotropic expansion of biological samples with easily tunable expansion ratio (up to eightfold). This method allows for simple and flexible expansion of a wide range of biological samples, from bacteria to human brain tissues, for super‐resolution imaging of samples with ordinary microscopes.