Biohybrid Circuits: Biofunctionalized Materials Featuring Feedforward and Feedback Circuits Exemplified by the Detection of Botulinum Toxin A (Adv. Sci. 4/2019) | Zendy

Wagner Hanna J. | Zendy; Kemmer Svenja | Zendy; Engesser Raphael | Zendy; Timmer Jens | Zendy; Weber Wilfried | Zendy

Open Access

Biohybrid Circuits: Biofunctionalized Materials Featuring Feedforward and Feedback Circuits Exemplified by the Detection of Botulinum Toxin A (Adv. Sci. 4/2019)

Author(s) -

Wagner Hanna J.,

Kemmer Svenja,

Engesser Raphael,

Timmer Jens,

Weber Wilfried

Publication year - 2019

Publication title -

advanced science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 5.388

H-Index - 100

ISSN - 2198-3844

DOI - 10.1002/advs.201970020

Subject(s) - electronic circuit , feed forward , stimulus (psychology) , network topology , nanotechnology , computer science , botulinum toxin , materials science , neuroscience , engineering , biology , control engineering , psychology , electrical engineering , psychotherapist , operating system

In article number 1801320 , Wilfried Weber and co‐workers present the incorporation of biological circuits into polymer materials capable of sensing and processing an input stimulus and producing a quantitative output. Positive feedback and/or feedforward network topologies detect the proteolytic activity of botulinum toxin A with adjustable kinetics and dynamic range. Image credit: Jo Richers ( www.jorichers.com ).

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