Open AccessNanoparticles: A Broad‐Spectrum ROS‐Eliminating Material for Prevention of Inflammation and Drug‐Induced Organ Toxicity (Adv. Sci. 10/2018)
Author(s) -
Li Lanlan,
Guo Jiawei,
Wang Yuquan,
Xiong Xiaoxing,
Tao Hui,
Li Jin,
Jia Yi,
Hu Houyuan,
Zhang Jianxiang
Publication year - 2018
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201870065
Subject(s) - inflammation , oxidative stress , reactive oxygen species , broad spectrum , drug , pathogenesis , pharmacology , medicine , immunology , chemistry , biochemistry , combinatorial chemistry
Uncontrolled inflammation contributes to the pathogenesis of numerous diseases. Scavenging of reactive oxygen species (ROS) is promising for treatment of inflammatory diseases. To circumvent current limitations, in article number 1800781 , Jianxiang Zhang and co‐workers report a material with broad‐spectrum ROS‐eliminating capability. A nanotherapy derived from this bioactive material shows superior efficacies in different mouse models of inflammation and oxidative stress injury.