Open AccessCancer Treatment: Enhanced Photodynamic Cancer Treatment by Mitochondria‐Targeting and Brominated Near‐Infrared Fluorophores (Adv. Sci. 3/2018)
Author(s) -
Noh Ilkoo,
Lee DaeYong,
Kim Heegon,
Jeong ChanUk,
Lee Yunsoo,
Ahn JungOh,
Hyun Hoon,
Park JiHo,
Kim YeuChun
Publication year - 2018
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201870012
Subject(s) - photodynamic therapy , singlet oxygen , mitochondrion , cancer , reactive oxygen species , apoptosis , mechanism (biology) , cancer research , cancer treatment , cancer cell , chemistry , biophysics , medicine , biology , oxygen , biochemistry , physics , organic chemistry , quantum mechanics
The photodynamic therapy effect and mechanism of mitochondria targeting photodynamic therapeutic agents (MitDt) are reported. The MitDt is taken in by the cancer mitochondria and subsequently releases singlet oxygen ( O12 ) when irradiated with a 662 nm laser, thereby inducing apoptosis of cancer. The underlying mechanism is discussed in article number 1700481 by Yeu‐Chun Kim and co‐workers.