Open AccessExtracellular Vesicles: Modularized Extracellular Vesicles: The Dawn of Prospective Personalized and Precision Medicine (Adv. Sci. 2/2018)
Author(s) -
Tao ShiCong,
Guo ShangChun,
Zhang ChangQing
Publication year - 2018
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201870007
Subject(s) - extracellular vesicles , vesicle , nucleic acid , extracellular vesicle , modular design , lipid bilayer , nanotechnology , personalized medicine , function (biology) , microbiology and biotechnology , chemistry , microvesicles , biophysics , bioinformatics , biology , membrane , computer science , biochemistry , materials science , microrna , gene , operating system
Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles that consist of a lipid bilayer enclosing proteins and nucleic acids. They are active in intercellular communications. As reviewed by Shang‐Chun Guo, Chang‐Qing Zhang, and co‐workers in article number 1700449 , attempts have been made to modify or improve almost all the components of EVs, including the lipid bilayer, the proteins, and the nucleic acids, thus launching a new era in modularized EV therapy through the modular design of EV components. Modularized EVs have highly customized modular design components related to biological function and targeted delivery, and they are proposed as a promising approach to achieve personalized and precision medicine.