Open AccessPhotosensitizer‐Anchored 2D MOF Nanosheets as Highly Stable and Accessible Catalysts toward Artemisinin Production
Author(s) -
Wang Ying,
Feng Liang,
Pang Jiandong,
Li Jialuo,
Huang Ning,
Day Gregory S.,
Cheng Lin,
Drake Hannah F.,
Wang Ye,
Lollar Christina,
Qin Junsheng,
Gu Zhiyuan,
Lu Tongbu,
Yuan Shuai,
Zhou HongCai
Publication year - 2019
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201802059
Subject(s) - photosensitizer , artemisinin , catalysis , materials science , chemical engineering , nanotechnology , photochemistry , chemistry , combinatorial chemistry , organic chemistry , plasmodium falciparum , malaria , immunology , biology , engineering
Abstract 2D metal–organic frameworks (2D‐MOFs) have recently emerged as promising materials for gas separations, sensing, conduction, and catalysis. However, the stability of these 2D‐MOF catalysts and the tunability over catalytic environments are limited. Herein, it is demonstrated that 2D‐MOFs can act as stable and highly accessible catalyst supports by introducing more firmly anchored photosensitizers as bridging ligands. An ultrathin MOF nanosheet‐based material, Zr‐BTB (BTB = 1,3,5‐tris(4‐carboxyphenyl)benzene), is initially constructed by connecting Zr 6 ‐clusters with the tritopic carboxylate linker. Surface modification of the Zr‐BTB structure was realized through the attachment of porphyrin‐based carboxylate ligands on the coordinatively unsaturated Zr metal sites in the MOF through strong Zr‐carboxylate bond formation. The functionalized MOF nanosheet, namely PCN‐134‐2D, acts as an efficient photocatalyst for 1 O 2 generation and artemisinin production. Compared to the 3D analogue (PCN‐134‐3D), PCN‐134‐2D allows for fast reaction kinetics due to the enhanced accessibility of the catalytic sites within the structure and facile substrate diffusion. Additionally, PCN‐134(Ni)‐2D exhibits an exceptional yield of artemisinin, surpassing all reported homo‐ or heterogeneous photocatalysts for the artemisinin production.