Open AccessRecent Advances on Functionalized Upconversion Nanoparticles for Detection of Small Molecules and Ions in Biosystems
Author(s) -
Gu Bin,
Zhang Qichun
Publication year - 2018
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201700609
Subject(s) - nanotechnology , photon upconversion , autofluorescence , nanoparticle , materials science , molecule , energy transfer , lanthanide , quantum dot , fluorescence , luminescence , förster resonance energy transfer , hydrogen sulfide , lead sulfide , ion , photochemistry , chemistry , sulfur , optoelectronics , organic chemistry , physics , quantum mechanics , molecular physics , metallurgy
Significant progress on upconversion‐nanoparticle (UCNP)‐based probes is witnessed in recent years. Compared with traditional fluorescent probes (e.g., organic dyes, metal complexes, or inorganic quantum dots), UCNPs have many advantages such as non‐autofluorescence, high chemical stability, large light‐penetration depth, long lifetime, and less damage to samples. This article focuses on recent achievements in the usage of lanthanide‐doped UCNPs as efficient probes for biodetection since 2014. The mechanisms of upconversion as well as the luminescence resonance energy transfer process is introduced first, followed by a detailed summary on the recent researches of UCNP‐based biodetections including the detection of inorganic ions, gas molecules, reactive oxygen species, and thiols and hydrogen sulfide.