Open AccessDrug Delivery: Lanthanide‐Doped Upconversion Nanoparticles: Emerging Intelligent Light‐Activated Drug Delivery Systems (Adv. Sci. 7/2016)
Author(s) -
Bagheri Ali,
Arandiyan Hamidreza,
Boyer Cyrille,
Lim May
Publication year - 2016
Publication title -
advanced science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.388
H-Index - 100
ISSN - 2198-3844
DOI - 10.1002/advs.201670035
Subject(s) - photon upconversion , drug delivery , materials science , nanotechnology , nanoparticle , lanthanide , energy transfer , doping , visible spectrum , laser , photochemistry , optoelectronics , ion , chemistry , optics , organic chemistry , physics , molecular physics
Cyrille Boyer, May Lim, and co‐workers highlight recent advances in upconversion nanoparticles (UCNPs) as NIR‐initiated controlled drug delivery systems. Surface modification strategies are reviewed alongside with the influence of the laser power intensity and illumination time on the drug release pattern in article 1500437. NIR‐to‐UV/visible UCNPs have emerged as potential remote‐controlled nanotransducers to generate in situ UV/visible light in order to activate the photoreaction of photoresponsive molecules for drug delivery applications. The cover design represents the mechanism of upconverting process by energy transfer between doped lanthanide ions in the upconversion nanoplatforms using NIR laser as excitation source and generation of UV/visible light.