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Single Live Cell Imaging: Simulation Assisted Nanoscale Imaging of Single Live Cells with Scanning Electrochemical Microscopy (Adv. Theory Simul. 2/2019)
Author(s) -
Filice Fraser P.,
Li Michelle S. M.,
Ding Zhifeng
Publication year - 2019
Publication title -
advanced theory and simulations
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.068
H-Index - 17
ISSN - 2513-0390
DOI - 10.1002/adts.201970005
Subject(s) - scanning electrochemical microscopy , nanoscopic scale , electrode , scanning ion conductance microscopy , materials science , nanometre , live cell imaging , microscopy , scanning probe microscopy , membrane , electrochemistry , nanotechnology , electrochemical cell , scanning electron microscope , cell , scanning confocal electron microscopy , chemistry , optics , physics , composite material , biochemistry
Nanoscale imaging of a single live cell by scanning electrochemical microscopy (SECM) is realized by Zhifeng Ding and co‐workers in article number 1800124 by simply scanning a nanometer electrode across the surface of the cell. The resulting faradaic current is simulated with a 3‐dimensional model. Cell surface topography, electrode‐to‐cell distance, and cell membrane can be quantified by fitting the experimental results, as is illustrated by the cross‐section curve shown on the cover.