Discovery of Small Anti‐ACE2 Peptides to Inhibit SARS‐CoV‐2 Infectivity (Adv. Therap. 7/2021) | Zendy

Adhikary Pratik | Zendy; Kandel Sashi | Zendy; Mamani UmarFarouk | Zendy; Mustafa Bahaa | Zendy; Hao Siyuan | Zendy; Qiu Jianming | Zendy; Fetse John | Zendy; Liu Yanli | Zendy; Ibrahim Nurudeen Mohammed | Zendy; Li Yongren | Zendy; Lin ChienYu | Zendy; Omoscharka Evanthia | Zendy; Cheng Kun | Zendy

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Discovery of Small Anti‐ACE2 Peptides to Inhibit SARS‐CoV‐2 Infectivity (Adv. Therap. 7/2021)

Author(s) -

Adhikary Pratik,

Kandel Sashi,

Mamani UmarFarouk,

Mustafa Bahaa,

Hao Siyuan,

Qiu Jianming,

Fetse John,

Liu Yanli,

Ibrahim Nurudeen Mohammed,

Li Yongren,

Lin ChienYu,

Omoscharka Evanthia,

Cheng Kun

Publication year - 2021

Publication title -

advanced therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.125

0

ISSN - 2366-3987

DOI - 10.1002/adtp.202170016

Subject(s) - infectivity , classics , library science , philosophy , medicine , history , virology , computer science , virus

SARS‐CoV‐2 infects human cells by binding its spike protein to the human ACE2 receptor. Using a peptide biopanning strategy, the authors have discovered small anti‐ACE2 peptides that can effectively block the SARS‐CoV‐2/ACE2 interaction. The anti‐ACE2 peptides can be potentially used as prophylactic or therapeutic agents for SARS‐CoV‐2 and other ACE2‐mediated viruses. This is reported by Kun Cheng and co‐workers in article number 2100087.

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