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Epigenetic Gene Regulation: Epigenetic Therapies in the Precision Medicine Era (Adv. Therap. 8/2020)
Author(s) -
Leite Michel Lopes,
Oliveira Kamila Botelho Sampaio,
Cunha Victor Albuquerque,
Dias Simoni Campos,
da Cunha Nicolau Brito,
Costa Fabricio F.
Publication year - 2020
Publication title -
advanced therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2366-3987
DOI - 10.1002/adtp.202070019
Subject(s) - epigenetics , dna methylation , histone , gene , gene expression , biology , ezh2 , regulation of gene expression , h3k4me3 , medicine , computational biology , bioinformatics , genetics , promoter
In article number 1900184 Nicolau Brito da Cunha, Fabricio F. Costa and co‐workers review the current state of knowledge regarding the three main epigenetic mechanisms of gene regulation, which are DNA methylation, histone modification and non‐coding RNA expression. In addition, epigenetic therapies with “epidrugs” applied to precision medicine are discussed. This is a field that is receiving increased interest in the scientific community and in industry.