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Muscle Atrophy: Counteracting Muscle Atrophy on Earth and in Space via Nanofluidics Delivery of Formoterol (Adv. Therap. 7/2020)
Author(s) -
Ballerini Andrea,
Chua Corrine Ying Xuan,
Rhudy Jessica,
Susnjar Antonia,
Di Trani Nicola,
Jain Priya R.,
Laue Grit,
Lubicka Danuta,
ShiraziFard Yasaman,
Ferrari Mauro,
Stodieck Louis S.,
Cadena Samuel M.,
Grattoni Alessandro
Publication year - 2020
Publication title -
advanced therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2366-3987
DOI - 10.1002/adtp.202070014
Subject(s) - atrophy , drug delivery , muscle atrophy , formoterol , medicine , in vivo , nanofluidics , pharmacology , nanotechnology , materials science , biology , budesonide , corticosteroid , microbiology and biotechnology
In article number 2000014 Alessandro Grattoni and co‐workers present the first‐ever in vivo study of an implantable drug delivery device in microgravity aboard the International Space Station. In this unprecedented research endeavor, the muscle hypertrophic effect of nanofluidic‐mediated sustained low dose elution of formoterol is demonstrated in rodents in space as well as on Earth.