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Enhanced Cancer Therapy by Combining Radiation and Chemical Effects Mediated by Nanocarriers
Author(s) -
Denkova Antonia G.,
Liu Huanhuan,
Men Yongjun,
Eelkema Rienk
Publication year - 2020
Publication title -
advanced therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2366-3987
DOI - 10.1002/adtp.201900177
Subject(s) - nanocarriers , radiation therapy , cancer therapy , cancer , medicine , cancer treatment , medical physics , pharmacology , drug
Next to surgery, radiotherapy and chemotherapy are the two most commonly applied treatments against cancer. These therapies are often combined, but the therapeutic outcome is still limited. Nanocarriers may be the solution to many of the issues encountered when combining these therapies. In this review, the role of nanocarriers in combined radiotherapy and chemical cancer treatment is discussed, divided into four distinct strategy classes. For each strategy, examples of the literature are given to come eventually to conclusion on the possible translation to the clinic.