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Cell Membrane–Camouflaged Colloid Motors for Biomedical Applications
Author(s) -
Gao Changyong,
Lin Zhihua,
Lin Xiankun,
He Qiang
Publication year - 2018
Publication title -
advanced therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2366-3987
DOI - 10.1002/adtp.201800056
Subject(s) - colloid , membrane , nanotechnology , drug delivery , chemistry , neuroscience , biochemical engineering , materials science , biology , engineering , biochemistry
Natural cell membrane–camouflaged colloid motors can not only convert the surrounding environmental energy into directed movement but also possess the functions of natural cell membranes. They can autonomously move and are guided by exogenous (e.g., chemical fuel, light, magnetic field, and ultrasound) and endogenous (i.e., chemotaxis) stimuli. These biointerfacing colloid motors with efficient drug loading/transporting capacity, prolonged blood circulation, and antibiofouling and specific targeting abilities are expected to open up opportunities for various biomedical applications and are recognized as the next‐generation therapeutic systems. In this progress report, the authors highlight the recent progress in research on cell membrane–coated colloid motors, as well as their potential for biomedical applications. The limitations and challenges of these colloid motors for in vivo applications are also addressed.