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Recent Advance in Near‐Infrared (NIR) Imaging Probes for Cancer Theranostics
Author(s) -
Liu Yuxin,
Jia Qi,
Zhou Jing
Publication year - 2018
Publication title -
advanced therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.125
0ISSN - 2366-3987
DOI - 10.1002/adtp.201800055
Subject(s) - photoacoustic imaging in biomedicine , photothermal therapy , near infrared spectroscopy , luminescence , photon upconversion , materials science , cancer imaging , absorbance , cancer , optoelectronics , nanotechnology , biomedical engineering , optics , medicine , physics
With the advantages of low biofluid scattering and minimal absorbance, light in a second near‐infrared window (NIR II, 1000–1700 nm) either as a signal or as an excitation source is preferred for bioimaging and disease diagnosis, especially for cancer theranostics. Due to recent advances in chemical synthesis and imaging techniques, various NIR II probes have been evaluated for tumor luminescence image‐guided cancer therapy and surgery. Furthermore, probes emitting optical, acoustic, or thermal signals under NIR II excitation have also been developed for upconversion luminescence, photoacoustic, and photothermal imaging of tumors. Herein, recent advances in the use of NIR II imaging probes in cancer theranostic applications are summarized along with future perspectives.