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Front Cover Picture: Zirconium Oxide‐Catalyzed Direct Amidation of Unactivated Esters under Continuous‐Flow Conditions (Adv. Synth. Catal. 10/2021)
Author(s) -
Rashed Md. Nurnobi,
Masuda Koichiro,
Ichitsuka Tomohiro,
Koumura Nagatoshi,
Sato Kazuhiko,
Kobayashi Shū
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202100451
Subject(s) - chemistry , amide , front cover , catalysis , zirconium , oxide , amine gas treating , medicinal chemistry , cover (algebra) , organic chemistry , mechanical engineering , engineering
The front cover picture illustrates that N ‐hexylbenzamide is produced by flow. It depicts that the methyl benzoate and n ‐hexylamine as starting materials flow from upstream, and they react with each other to form an amide product by passing through pebbles that stand for the zirconium oxide catalysts. The new flow system enables direct reaction of fundamental substrates, carboxylic acid ester and amine, to realize green chemistry such as low environment load, high efficiency substance conversion, and safe process. Details can be found in the Communication by Md. Nurnobi Rashed, Koichiro Masuda, Tomohiro Ichitsuka, Nagatoshi Koumura, Kazuhiko Sato, and Shū Kobayashi (M. N. Rashed, K. Masuda, T. Ichitsuka, N. Koumura, K. Sato, S. Kobayashi, Adv. Synth. Catal . 2021 , 363 , 2529–2535; DOI: 10.1002/adsc.202001496).