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Manganese Catalyzed Hydrogenation of Azo (N=N) Bonds to Amines
Author(s) -
Das Uttam Kumar,
Kar Sayan,
BenDavid Yehoshoa,
DiskinPosner Yael,
Milstein David
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202100440
Subject(s) - chemistry , catalysis , manganese , hydrazine (antidepressant) , ligand (biochemistry) , pincer movement , metal , reaction mechanism , organic chemistry , combinatorial chemistry , photochemistry , biochemistry , receptor , chromatography
We report the first example of homogeneously catalyzed hydrogenation of the N=N bond of azo compounds using a complex of an earth‐abundant‐metal. The hydrogenation reaction is catalyzed by a manganese pincer complex, proceeds under mild conditions, and yields amines, which makes this methodology a sustainable alternative route for the conversion of azo compounds. A plausible mechanism involving metal‐ligand cooperation and hydrazine intermediacy is proposed based on mechanistic studies.