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Front Cover Picture: Kinetic Resolution of α‐Silyl‐Substituted Allylboronate Esters via Chemo‐ and Stereoselective Allylboration of Aldehydes (9/2021)
Author(s) -
Park Jinyoung,
Jung Yongsuk,
Kim Jeongho,
Lee Eunsung,
Lee Sarah Yunmi,
Cho Seung Hwan
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202100350
Subject(s) - chemistry , silylation , kinetic resolution , stereoselectivity , enantiomer , front cover , enantioselective synthesis , medicinal chemistry , stereochemistry , catalysis , organic chemistry , cover (algebra) , mechanical engineering , engineering
The front cover picture , provided by Seung Hwan Cho and co‐workers, illustrates ( R )‐TRIP‐catalyzed kinetic resolution of α‐silyl‐substituted allylboronate esters through chemo‐, diastereo‐, and enantioselective allylation of aldehydes. The reaction is proposed to proceed via a chair‐like transition state by the double coordination of ( R )‐TRIP to the C−H bond of aldehydes and the oxygen atom of Bpin group, thus effectively resolving α‐silyl‐substituted allylboronate esters with high enantiomeric ratios. Details can be found in the communication by Seung Hwan Cho and co‐workers (J. Park, Y. Jung, J. Kim, E. Lee, S. Y. Lee, S. H. Cho, Adv. Synth. Catal . 2021 , 363 , 2371–2376; DOI: 10.1002/adsc.202001170).