A Photoinduced Multicomponent Regioselective Synthesis of 1,4,5‐Trisubstituted‐1,2,3‐Triazoles: Transition Metal‐, Azide‐ and Oxidant‐Free Protocol | Zendy

Sai Allaka Bhargava | Zendy; Basavoju Srinivas | Zendy; Rama Krishna Gamidi | Zendy

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A Photoinduced Multicomponent Regioselective Synthesis of 1,4,5‐Trisubstituted‐1,2,3‐Triazoles: Transition Metal‐, Azide‐ and Oxidant‐Free Protocol

Author(s) -

Sai Allaka Bhargava,

Basavoju Srinivas,

Rama Krishna Gamidi

Publication year - 2021

Publication title -

advanced synthesis and catalysis

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.541

H-Index - 155

eISSN - 1615-4169

pISSN - 1615-4150

DOI - 10.1002/adsc.202100321

Subject(s) - chemistry , regioselectivity , azide , isatin , transition metal , combinatorial chemistry , schiff base , organic chemistry , stereochemistry , catalysis

A transition metal‐ and azide‐free approach is explored to synthesize 1,4,5‐trisubstituted‐1,2,3‐triazoles under sunlight. The reaction proceeds via C−N and N−N bond formations. These regioselective 1,2,3‐triazoles are obtained from isatin Schiff bases, benzaldehydes and tosylhydrazine in the presence of base. This protocol offers the structurally diverse 1,2,3‐triazole derivatives with 75–90% yields.

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