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Palladium‐Catalyzed Thiocarbonylation of Benzyl Chlorides with Sulfonyl Chlorides for the Synthesis of Arylacetyl Thioesters
Author(s) -
Wang Wei,
Qi Xinxin,
Wu XiaoFeng
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202100112
Subject(s) - chemistry , sulfonyl , palladium , catalysis , sulfur , organic chemistry , combinatorial chemistry , alkyl
A convenient procedure for the synthesis of thioesters has been developed via a palladium‐catalyzed thiocarbonylation of benzyl chlorides with sulfonyl chlorides. Various arylacetyl thioesters were produced in good yields by using sulfonyl chlorides as an odorless sulfur source. Furthermore, W(CO) 6 exhibited dual roles as both a solid CO surrogate and reductant here.