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De Novo Construction of Substituted Terephthalates via Phosphine Catalyzed Domino Benzannulation Reactions
Author(s) -
Wang Dan,
Lin Junhui,
Zhu Yannan,
Huang You
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202001513
Subject(s) - domino , chemistry , phosphine , catalysis , yield (engineering) , cascade reaction , combinatorial chemistry , reaction conditions , organic chemistry , materials science , metallurgy
The robustness of phosphine catalysis enabling the domino benzannulation reactions of allenoates with enamines is described. A broad array of substituted terephthalates were delivered under simple and practical reaction conditions. Furthermore, the reaction could be carried out on a gram scale with higher yield, and various conversions of the terephthalate products demonstrate the versatility of this transformation.