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Synthesis of Oxazolidinones by a Hypervalent Iodine Mediated Cyclization of N ‐Allylcarbamates
Author(s) -
Das Mirdyul,
Rodríguez Arantxa,
Lo Pui Kin Tony,
Moran Wesley J.
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202001451
Subject(s) - hypervalent molecule , chemistry , iodine , enantioselective synthesis , derivatization , combinatorial chemistry , iodine compounds , organic chemistry , catalysis , high performance liquid chromatography
The preparation of oxazolidinones by the hypervalent iodine mediated cyclization of allylcarbamates is described. A versatile range of substrates can be converted into substituted oxazolidinones primed for further transformations. Derivatization of the products at both ends is demonstrated. A preliminary attempt at the enantioselective formation of an oxazolidinone using a chiral iodane is also presented.