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Visible‐Light‐Promoted Switchable Synthesis of C‐3‐Functionalized Quinoxalin‐2(1 H )‐ones
Author(s) -
Aganda Kim Christopher C.,
Hong Boseok,
Lee Anna
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202001396
Subject(s) - chemistry , reagent , visible spectrum , photocatalysis , fluorescence , catalysis , perchlorate , photochemistry , combinatorial chemistry , metal , organic chemistry , ion , physics , optoelectronics , quantum mechanics
Abstract A visible‐light‐promoted synthesis of quinoxalin‐2(1 H )‐ones has been developed using 9‐mesityl‐10‐methylacridinium perchlorate as an organo‐photocatalyst. The atmosphere‐controlled method (Ar/air) enabled the selective synthesis of hydroxyl‐ and acyl‐containing quinoxalin‐2(1 H )‐ones under mild reaction conditions without the use of any metal catalysts or toxic reagents. A fluorescent labelling experiment showed that hydroxyl‐containing quinoxalin‐2(1 H )‐ones may have utility in various biological applications as potent fluorophores.