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Sulfoximines with α ‐Ketoester Functionalities at Nitrogen from Cyanoacetates and Air
Author(s) -
Wang Chenyang,
Wang Han,
Bolm Carsten
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202001264
Subject(s) - chemistry , hypervalent molecule , iodobenzene , electrophile , reagent , organic chemistry , nitrogen , iodine , trifluoromethylation , alkyl , catalysis , trifluoromethyl
Sulfoximines with nitrogen‐bound α‐ketoester units are efficiently prepared by an operationally simple one‐pot reaction sequence in air starting from methoxy(mesyloxy)iodobenzene, N H‐sulfoximines, and cyanoacetates. Key of the process is the in‐situ formation of hypervalent iodine reagents, which serve as electrophilic sulfoximidoyl sources.