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Reactions of Organophosphorus Compounds with Arynes: Reactivity and Mechanism
Author(s) -
Chen Jian,
Fan Rong,
Liu Zhijian,
Tan Jiajing
Publication year - 2021
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202001237
Subject(s) - chemistry , aryne , reactivity (psychology) , mechanism (biology) , combinatorial chemistry , computational chemistry , organic chemistry , pathology , epistemology , medicine , philosophy , alternative medicine
Aryl phosphorus compounds have found versatile applications in materials, medicinal and synthetic chemistry. As a powerful tool, aryne chemistry has been widely utilized in constructing aryl C−P bonds under mild conditions; this has enabled facile access to a variety of structurally diverse aryl–phosphorus compounds with good efficiency. The present review aims to offer a comprehensive overview of the chemistry between arynes and organophosphorus compounds, with emphasis placed on reactivity modes and mechanistic aspects. According to the valency of phosphorus atoms, this paper is divided into two main sections, reactions of arynes with organophosphorus(III) compounds and those with organophosphorus(V) compounds.