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Front Cover Picture: HFIP‐Mediated Decarboxylative [4+3]‐Annulation of Azaoxyallyl Cations with Isatoic Anhydride (Adv. Synth. Catal. 17/2020)
Author(s) -
Kim Eunjin,
Lee Chang Yoon,
Kim SungGon
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000800
Subject(s) - annulation , chemistry , front cover , yield (engineering) , cascade , intramolecular force , medicinal chemistry , cover (algebra) , organic chemistry , catalysis , materials science , mechanical engineering , chromatography , engineering , metallurgy
The front cover picture , provided by Sung‐Gon Kim and his co‐workers, illustrates an efficient [4+3]‐annulation reaction between in situ generated azaoxyallyl cations and isatoic anhydride to afford seven‐membered 1,4‐benzodiazepinediones. This annulation involves the cascade reaction of decarboxylative addition of hexafluoroisopropanol (HFIP) to isatoic anhydride, addition to the azaoxyallyl cation generated from α‐halohydroxamate, and intramolecular substitution to yield 1,4‐benzodiazepinediones. Details of this work can be found in the full paper on pages 3594–3603 (E. Kim, C. Y. Lee, S.‐G. Kim, Adv. Synth. Catal . 2020 , 362 , 3594–3603; DOI: 10.1002/adsc.202000439).