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Catalytic Aerobic Dehydrogenatin of N ‐Heterocycles by N ‐Hydoxyphthalimide
Author(s) -
Chen Weidong,
Tang Hao,
Wang Weilin,
Fu Qiang,
Luo Junfei
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000767
Subject(s) - dehydrogenation , chemistry , catalysis , copper , combinatorial chemistry , organic chemistry , medicinal chemistry
Catalytic methods for the aerobic dehydrogenation of N ‐heterocycles are reported. In most cases, indoles are accessed efficiently from indolines using catalytic N ‐hydroxyphthalimide (NHPI) as the sole additive under air. Further studies revealed an improved catalytic system of NHPI and copper for the preparation of other heteroaromatics, for example quinolines.