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Methods of Nitriles Synthesis from Amines through Oxidative Dehydrogenation
Author(s) -
Patil Rajendra D.,
Gupta Maneesh Kumar
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000635
Subject(s) - dehydrogenation , chemistry , nitrile , ruthenium , catalysis , combinatorial chemistry , transition metal , mesoporous material , organic chemistry , photochemistry
In recent years, oxidative dehydrogenation (ODH) of amines has proven to be an efficient, clean and fundamental route for the synthesis of nitriles. This review focuses on the different types of reactions for the oxidation of amines to nitriles such as transition metal‐catalysis, photoactivation, acceptorless dehydrogenation, nitroxyl radical‐mediated, and N,O‐doped mesoporous carbon. Emphasis is placed on the ODH of amines to the corresponding nitriles using ruthenium catalysts. Metal free systems utilizing iodine, TEMPO and its derivatives, TCCA with or without additives are also discussed. The ODH of amines using N,O‐doped mesoporous carbon is elaborated. Attention is also given to major improvements, achievements, and challenges that still remain in the field of nitrile synthesis from amines.