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Recent Advances in Radical C−H Bond Functionalization of Imidazoheterocycles
Author(s) -
Patel Om P. S.,
Nandwaitesh K.,
Legoabe Lesetja J.,
Das Bhaskar C.,
Kumar Anil
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000633
Subject(s) - chemistry , surface modification , pyrazine , thiazole , isoquinoline , reagent , radical , pyridine , catalysis , quinoline , combinatorial chemistry , pyrimidine , medicinal chemistry , organic chemistry , stereochemistry
Direct C−H bond functionalization through radical pathway has emerged as a powerful and ideal strategy for the synthesis of organic compounds. This review provides an overview of recent developments in radical C−H functionalization of imidazoheterocycles such as imidazo[1,2‐ a ]pyridine, benzo[ d ]imidazo[2,1‐ b ]thiazole, imidazo[2,1‐ b ]thiazole, imidazo[1,2‐ a ]pyrimidine, imidazo[2,1‐ a ]isoquinoline, imidazo[1,2‐ a ]pyrazine and imidazo[1,2‐ a ]quinoline using organic peroxides, photo/electric‐induced protocols, iodine‐based reagents, first‐row transition metal catalysts (Fe, Mn, Ni and Cu) and inorganic oxidants/or salts.