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Disulfide Promoted C−P Bond Cleavage of Phosphoramide: “P” Surrogates to Synthesize Phosphonates and Phosphinates
Author(s) -
Hou Fei,
Du XingPeng,
Alduma Anwar I.,
Li ZhiFeng,
Huo CongDe,
Wang XiCun,
Wu XiaoFeng,
Quan ZhengJun
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000511
Subject(s) - chemistry , phosphinate , phosphine , phosphonate , cleavage (geology) , alkyl , bond cleavage , disulfide bond , organic chemistry , stereochemistry , medicinal chemistry , catalysis , biochemistry , geotechnical engineering , fire retardant , fracture (geology) , engineering
A metal‐free C−P bond cleavage reaction is described herein. Phosphoramides, a phosphine source, can react with alcohols to produce phosphonate and phosphinate derivatives in the presence of a disulfide. P−H 2 , P‐alkyl, and P,P‐dialkyl phosphoramides can be used as substrates to obtain the corresponding pentavalent phosphine products.