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Iridium(I) Complexes with Anionic N‐Heterocyclic Carbene Ligands as Catalysts for H/D Exchange in Nonpolar Media
Author(s) -
Koneczny Marvin,
Phong Ho Luong,
Nasr Alexandre,
Freytag Matthias,
Jones Peter G.,
Tamm Matthias
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000438
Subject(s) - chemistry , iridium , pyridine , carbene , moiety , intramolecular force , catalysis , cyclohexane , borylation , medicinal chemistry , phosphine , cyclooctadiene , dichloromethane , polymer chemistry , solvent , organic chemistry , photochemistry , alkyl , aryl
A series of neutral iridium(I) complexes of the general type [(WCA−NHC)]IrL(COD)] (COD=1,5‐cyclooctadiene; L=phosphine, pyridine), bearing anionic N‐heterocyclic carbenes (WCA−NHC) with a weakly coordinating anionic (WCA) borate moiety, were prepared by addition of phosphines and pyridine to [(WCA−NHC)]Ir(COD)], in which the available coordination site is stabilized by intramolecular metal‐arene interaction (π‐face donation). The solvent and substrate scope of the neutral complexes as catalysts for H/D exchange was investigated, revealing their suitability for promoting efficient deuteration in nonpolar solvents such as cyclohexane.