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Aerobic Oxidative Functionalization of Indoles
Author(s) -
Liu Saiwen,
Zhao Feng,
Chen Xing,
Deng GuoJun,
Huang Huawen
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000285
Subject(s) - chemistry , surface modification , indole test , oxidative phosphorylation , combinatorial chemistry , molecular oxygen , organic chemistry , nanotechnology , oxygen , biochemistry , materials science
The synthetic methodology for direct indole functionalizations is of great significance in indole chemistry and has been intensively investigated in the last few decades. From the perspective of green chemistry, oxygen is the best choice as the terminal oxidant in molecular synthesis. Hence, aerobic oxidative functionalization of indoles became a hot research topic in the last decade. Numerous efficient protocols in this field have been discovered that enable facile and efficient transformations of indoles to related valuable compounds, which are summarized and discussed in detail in this review.