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Rhodium(III)‐Catalyzed Oxidative C(sp 3 )−H Alkenylation of 8‐Methylquinolines with Maleimides Under Aerobic Conditions
Author(s) -
Shan Baode,
Kang Baotao,
Song Mingyue,
Wang Rui,
Chen Guozhu,
Li Cuncheng,
Zhao Huaiqing
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000283
Subject(s) - chemistry , rhodium , catalysis , oxidative phosphorylation , copper , oxygen , medicinal chemistry , organic chemistry , biochemistry
A rhodium(III)‐catalyzed C(sp 3 )−H alkenylation of 8‐methylquinolines with electron‐deficient maleimides has been accomplished with the combination of copper acetate, 2,2,6,6‐tetramethylpiperidine‐1‐oxyl and oxygen as the oxidant. A variety of maleimides react with various 8‐methylquinolines to furnish the corresponding alkenylated products in moderate to good yields.