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Front Cover Picture: Tandem Access to Acridones and their Fused Derivatives: [1+2+3] Annulation of Isocyanides with Unsaturated Carbonyls (Adv. Synth. Catal. 12/2020)
Author(s) -
Zhang LingJuan,
Yang Wenhui,
Hu Zhongyan,
Zhang XianMing,
Xu Xianxiu
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000262
Subject(s) - chemistry , annulation , aromatization , cycloaddition , isocyanide , domino , tandem , intramolecular force , ring (chemistry) , stereochemistry , medicinal chemistry , organic chemistry , catalysis , materials science , composite material
The front cover picture , provided by Xianxiu Xu and co‐workers, illustrates a double annulation of o ‐enoyl arylisocyanides with α,β‐unsaturated carbonyl compounds under metal‐free conditions, which allows the efficient construction of a wide range of acridones and their cyclo[ b ]fused derivatives. This practical protocol features a one‐pot domino process involving an isocyanide‐based [1+4] cycloaddition, an aminofuran‐based intramolecular [4+2] cycloaddition, ring opening and aromatization. Details of this work can be found in the full paper on pages 2379–2384 (L.‐J. Zhang, W. Yang, Z. Hu, X.‐M. Zhang, X. Xu, Adv. Synth. Catal . 2020 , 362 , 2379–2384; DOI: 10.1002/adsc.201901560).