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Al(OTf) 3 ‐Catalyzed Tandem Coupling Reaction between N,N ‐Disubstituted Aminomalonitriles and Substituted Arenes: a Synthesis of 1‐Cyano‐bisindolylmethane Analogues ≠
Author(s) -
Lei LinSheng,
Wang BoWen,
Jin DaPing,
Gao ZhuPeng,
Wang ShaoHua,
Xu XueTao,
Zhang Kun,
Zhang XiaoYun
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.202000261
Subject(s) - chemistry , tandem , catalysis , combinatorial chemistry , molecule , coupling (piping) , coupling reaction , computational chemistry , stereochemistry , medicinal chemistry , organic chemistry , mechanical engineering , materials science , engineering , composite material
A synthesis of 1‐cyano‐bisindolylmethane analogues via an Al(OTf) 3 ‐catalyzed tandem coupling reaction between N,N ‐disubstituted aminomalonitriles and substituted arenes has been developed. This method not only provides an alternative synthetic strategy for the synthesis of corresponding functional molecules, but also enriches the volume of bisarylmethanes library to facilitate related functional studies.