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Intermolecular Iodofluoroalkylation of Unactivated Alkynes and Alkenes Mediated by Manganese Catalysts
Author(s) -
Ji YunXing,
Wang LuJun,
Guo WeiSi,
Bi Qirui,
Zhang Bo
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201901556
Subject(s) - chemistry , manganese , catalysis , functional group , combinatorial chemistry , intermolecular force , compatibility (geochemistry) , alkyl , organic chemistry , molecule , chemical engineering , engineering , polymer
An approach for iodofluoroalkylation of unactivated alkynes and alkenes facilitated by an earth‐abundant and inexpensive manganese catalyst, Mn 2 (CO) 10 , is reported. This protocol employs visible light as the energy input and shows a wide substrate scope and high functional‐group compatibility. A variety of synthetically useful fluoroalkylated alkyl and alkenyl iodides can be prepared in moderate to excellent yields. The reaction features high efficiency, operational simplicity, scalability, as well as excellent chemo‐, regio‐, and E / Z selectivities.