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Blue Light‐Promoted N−H Insertion of Carbazoles, Pyrazoles and 1,2,3‐Triazoles into Aryldiazoacetates
Author(s) -
Stivanin Mateus L.,
Fernandes Alessandra A. G.,
Silva Amanda F.,
Okada Celso Y.,
Jurberg Igor D.
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201901343
Subject(s) - chemistry , blue light , irradiation , combinatorial chemistry , photochemistry , optoelectronics , physics , nuclear physics
Blue light irradiation of aryldiazoacetates leads to the formation of free carbenes, which can react with carbazoles, pyrazoles and 1,2,3‐triazoles to afford the corresponding N−H inserted products. These reactions are performed under air and at room temperature, allowing the mild preparation of a variety of motifs found in biologically relevant targets.
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