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Hypervalent Iodine(III)‐Promoted Rapid Cascade Reaction of Quinoxalinones with Unactivated Alkenes and TMSN 3
Author(s) -
Shen Jiabin,
Xu Jun,
Huang Lin,
Zhu Qing,
Zhang Pengfei
Publication year - 2020
Publication title -
advanced synthesis and catalysis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.541
H-Index - 155
eISSN - 1615-4169
pISSN - 1615-4150
DOI - 10.1002/adsc.201901314
Subject(s) - hypervalent molecule , chemistry , cascade , iodine , component (thermodynamics) , iodine compounds , combinatorial chemistry , cascade reaction , transformation (genetics) , organic chemistry , catalysis , chromatography , biochemistry , physics , gene , thermodynamics
The first example of rapidly three‐component cascade reaction of quinoxalinones with unactivated alkenes and TMSN 3 under mild condition has been described. This approach provides a practical solution for the rapid modification of quinoxalinones and enables new planning strategies for the synthesis of bioactive organoazides. A radical mechanism is responsible for this three‐component transformation.